https://www.fradeo.com/de/kandidaten/deutsch-franzoesische-stellenangebote/biotransformation-scientist-lab-head
Biotransformation Scientist – Lab Head
- Munich
- 20. November 2020
- Ref. FRDJOB2020112015542414
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AXEPTA SA
Established in 2009, AXEPTA Talents is a Swiss recruitment agency specializing in five key sectors.
We are looking for a Biotransformation Scientist – Lab Head for one of our clients, based near to Munich, to join its DMPK team and lead the engineers and laboratory technicians working on the biotransformation of small molecules and peptides.
Join a dynamic, international and fast-growing company in the CRO sector for Life Sciences.
Join a dynamic, international and fast-growing company in the CRO sector for Life Sciences.
Responsibilities:
You will have to investigate and work on the biotransformation of small molecules and peptides being part of discovery and development studies we perform for the CRO’s clients.
- Leading a small team of engineers/laboratory technicians and maintaining the laboratory environment and instruments
- Planning, executing, and reporting client-based metabolism experiments in the role as study director or responsible scientist
- Organizing and coordinating work and work packages within the laboratory in order to ensure optimal employment of resources as well as smooth and timely interaction with other departments and clients
- Ensuring adequate training of staff in order to further develop capabilities and strengths and ameliorate where gaps are identified
- Keeping abreast with current advances in MS including automation and applying new methodologies for increasing sensitivity, throughput, and for accelerating research to improve the quality of scientific data in drug development
- Evaluation and implementation of new technologies, techniques, and skills in accordance with the department strategy and following literature in the area of drug metabolism, metabolite identification, UPLC-MS, and radio detection
- Maintaining awareness of the latest developments in the area of drug metabolism and its relation to drug safetyCompliance with German law, GLP, and GCP guidelines as well as with other applicable regulations (e.g., radio protection) pertaining to the R&D process, study conduct, and registration of drugs.
- Enforcing adherence to safety measures in laboratories (accountable as per delegation)
Your profile :
- You have a PhD in biochemistry, chemistry, pharmacy, or a related field, with postdoctoral training or previous relevant experience in the pharmaceutical, biotech industry, or CRO (at least 5 years)
- Hands-on experiences in operating and maintaining UPLC and high-resolution mass spectrometric equipment for the purpose of metabolite identification and characterization of small molecules, peptides, oligonucleotides, or proteins
- In-depth experience and knowledge of drug metabolism as well as in the interpretation of mass spectral data for metabolite structure elucidation
- Hands-on experiences in working with radioactivity
- Experiences in leading small to mid-size teams
- Fluent in English and German
